Prostate cancer is one of the most prevalent cancers among men worldwide, particularly in the United States. According to the American Cancer Society, approximately one in eight men will be diagnosed with prostate cancer during their lifetime, with tens of thousands of men dying from the disease each year. Risk increases significantly with age, as roughly 60 percent of diagnoses occur in men over the age of 65. Additionally, men of African descent—including African American men and Caribbean men of African ancestry—experience higher incidence rates and often face more aggressive forms of the disease. These disparities highlight the importance of understanding both biological and lifestyle factors that may influence prostate cancer risk.
Over decades, researchers have investigated potential lifestyle influences on prostate health, including diet, exercise, hormone levels, and sexual activity. One area that has attracted attention is ejaculation frequency. Studies have suggested that sexual activity and regular ejaculation could play a role in maintaining prostate health, although findings have historically been limited or inconsistent. The need for large, long-term studies has been emphasized to clarify whether ejaculation frequency is associated with measurable changes in prostate cancer risk.
A landmark study published in European Urology in 2016 examined nearly 32,000 men over an 18-year period, from 1992 to 2010, to explore the relationship between ejaculation frequency and prostate cancer risk. Participants were asked to report their frequency of ejaculation at various stages of adulthood, including in their 20s, 40s, and current age at the time of reporting. This longitudinal approach allowed researchers to examine patterns over a significant portion of adult life, reducing the reliance on short-term or cross-sectional data that might be more susceptible to bias.
The study found that men who reported higher ejaculation frequency—defined as 21 or more times per month—were significantly less likely to be diagnosed with prostate cancer than men reporting lower frequency, such as four to seven times per month. The reduction in relative risk was approximately 20 percent, particularly for low-risk forms of prostate cancer. While the results were statistically significant, the authors emphasized that the study established an association rather than a definitive cause-and-effect relationship. Nonetheless, the size and duration of the study lend considerable weight to its findings.
Medical experts have described the research as some of the strongest evidence to date linking higher ejaculation frequency with potentially lower prostate cancer risk. Dr. Anne Calvaresi, chair of the Prostate Health Committee at the Urology Care Foundation, highlighted the study as particularly valuable in advancing understanding of prostate health while cautioning that the biological mechanisms remain unclear. One hypothesis suggests that frequent ejaculation may help clear substances from the prostate and seminal fluid that could accumulate over time, potentially reducing inflammation or other factors linked to cancer development.
However, researchers and clinicians stress that prostate cancer risk is influenced by multiple factors beyond sexual activity. Genetics, age, race, and overall health all play significant roles, and no single lifestyle behavior can eliminate risk entirely. While the study contributes an important perspective on a modifiable aspect of men’s health, it does not replace regular medical care, screening, or attention to symptoms.
Early-stage prostate cancer often produces no noticeable symptoms, which can delay detection. When symptoms do appear, they may include blood in the urine or semen, increased frequency of urination, difficulty starting or stopping urination, and waking frequently at night to urinate. Because early signs can be subtle, routine medical checkups and prostate-specific antigen (PSA) testing are critical for timely detection, particularly for men in higher-risk groups based on age, ancestry, or family history.
Advanced prostate cancer may manifest more severe or systemic symptoms. These can include urinary leakage, back or bone pain, erectile difficulties, persistent fatigue, unintended weight loss, and weakness in the arms or legs. Recognizing these symptoms early and consulting a healthcare provider promptly is essential for effective intervention, as treatments are more likely to be successful when cancer is detected at an earlier stage.
While the 2016 study highlights a potential protective role of frequent ejaculation, experts emphasize that lifestyle modifications alone are not a guarantee against prostate cancer. Men are encouraged to maintain balanced nutrition, regular physical activity, and healthy body weight, all of which contribute to overall cancer risk reduction. In addition, discussions with healthcare professionals about family history, screening options, and individualized risk factors are crucial components of prostate health management.
Importantly, the study reinforces the idea that sexual activity may be one factor among many that influence prostate cancer risk. While higher ejaculation frequency appears correlated with reduced likelihood of diagnosis, it should be viewed as complementary to, rather than a replacement for, evidence-based medical strategies for prevention and early detection.
The findings from the 2016 European Urology study contribute to a growing understanding of men’s prostate health and underscore the importance of long-term observational research. By identifying a possible link between ejaculation frequency and prostate cancer risk, the study provides a nuanced perspective that informs both public awareness and clinical guidance. However, experts caution that these results are associative and not definitive; further research is needed to explore the underlying mechanisms and to confirm findings in diverse populations.
Ultimately, the study adds an important dimension to broader conversations about men’s health, reinforcing the value of regular medical checkups, awareness of early warning signs, and healthy lifestyle habits. While no single behavior can completely prevent prostate cancer, integrating sexual health, lifestyle choices, and routine medical monitoring represents a comprehensive approach to maintaining prostate well-being throughout adulthood.