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Mouth cancer, also known as oral cancer, is a serious disease affecting the tissues of the mouth, tongue, lips, and throat. It falls under the broader category of head and neck cancers, which include cancers of the pharynx, larynx, and other oral structures. The disease often begins as a small lesion or sore in the mouth that fails to heal, but over time, it can invade surrounding tissues and spread to other parts of the body. Because of its location, mouth cancer can significantly impact essential functions such as speaking, swallowing, and eating, making early detection and treatment critical for improving survival rates and quality of life.

The prevalence of mouth cancer increases with age, with most cases occurring in individuals over the age of 40. While it can occur in younger people, the risk is considerably higher among older adults due to cumulative exposure to risk factors over time. Men are generally more susceptible to developing mouth cancer than women, a trend attributed to higher rates of tobacco and alcohol consumption among males in many regions. However, lifestyle changes and increasing tobacco use among women in certain areas have begun to narrow this gender gap, emphasizing the need for awareness and preventive measures across all demographics.

Several factors contribute to the development of mouth cancer. Tobacco use, whether through smoking or chewing, is the leading cause, significantly increasing the likelihood of malignant transformation in oral tissues. Alcohol consumption further compounds the risk, and the combination of tobacco and alcohol is particularly dangerous. Other risk factors include chronic irritation from poorly fitting dentures, human papillomavirus (HPV) infections, excessive sun exposure to the lips, and poor oral hygiene. Nutritional deficiencies and genetic predispositions may also play a role, highlighting the multifactorial nature of this disease and the importance of addressing both lifestyle and environmental contributors.

In India, the burden of mouth cancer is substantial. This year alone, a total of 77,003 new cases have been reported, illustrating the scale of the public health challenge. The disease is particularly prevalent in regions where tobacco chewing and smoking are widespread, and public awareness about oral cancer remains limited. Despite advances in medical care, late diagnosis remains a critical issue, as many patients only seek treatment after the disease has progressed, reducing the chances of successful outcomes. Public health initiatives focused on education, early screening, and lifestyle modification are crucial to reversing these trends.

The mortality associated with mouth cancer is also alarming. In the same year, 52,067 deaths were recorded due to this disease in India. High mortality rates are often linked to delayed diagnosis, limited access to specialized care, and lack of awareness about early warning signs such as persistent mouth sores, unexplained bleeding, or lumps. Early-stage detection significantly improves survival rates, but widespread barriers, including social stigma and inadequate healthcare infrastructure, prevent many individuals from receiving timely intervention. This highlights the urgent need for comprehensive oral cancer screening programs and community-level education initiatives.

Overall, mouth cancer represents a significant health challenge, particularly in countries like India where risk factors are prevalent, and public awareness is still developing. Men over 40 remain the most affected group, but changing lifestyle patterns suggest that broader demographics are increasingly at risk. Preventive measures, early detection, and access to effective treatment are essential to reducing both incidence and mortality. By understanding the risk factors, recognizing early symptoms, and seeking timely medical care, individuals can play a proactive role in combating this disease, while public health systems must work to ensure widespread education, screening, and support for affected populations.

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