Understanding the Link Between Breast and Ovarian Cancer
Breast and ovarian cancers are among the most common cancers affecting women, and they share important biological and genetic connections. A key link involves mutations in the BRCA1 and BRCA2 genes, which normally help repair DNA but, when mutated, significantly raise the risk of both cancers.
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BRCA1 mutations carry up to a 72% risk of breast cancer and 44% risk of ovarian cancer.
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BRCA2 mutations carry up to a 69% risk of breast cancer and 17% risk of ovarian cancer.
These mutations can be inherited from either parent, making family history crucial. Women with close relatives who had breast or ovarian cancer—especially at a young age—should consider genetic counseling and testing.
Other shared risk factors include age, hormone therapy, reproductive history, and having children later or not at all.
Why Knowing Matters:
Women at higher risk may benefit from increased screening, preventive surgeries, or medications to reduce cancer risk. Awareness of the connection between these cancers allows for earlier detection and better outcomes.
If you or your family have a history of breast or ovarian cancer, speak to a healthcare professional about genetic testing and personalized prevention plans. Early knowledge can save lives.